Abstract: Under the dual background of safeguarding national food security and promoting high-quality agricultural development, investigating the coordinative relationship between cultivated land use transition and grain production is of substantial practical significance. Taking 111 counties(cities and districts) of Guangxi Zhuang Autonomous Region as the study area, this paper constructs separate evaluation indicator systems for cultivated land use transition and grain production, and applies the entropy method, the coupling coordination degree model, the coordination influence model, and the geographical detector to systematically analyze the spatiotemporal evolution characteristics and driving factors of their coupling coordination from 2013 to 2023. The results indicate that:(1) During the study period, the cultivated land use transition index in Guangxi exhibits a trend of first declining and then rising, while the core concentration areas of high-value and low-value zones remain relatively stable; the grain production index fluctuates considerably, demonstrating an evolutionary pattern of first expanding and then narrowing.(2) The coupling coordination degree between the two systems is generally at a basic coordination stage; moderately coordinated areas are mainly concentrated in central, northeastern, and southeastern Guangxi, whereas moderately unbalanced areas are found in the central urban districts of prefecture-level cities and some coastal districts along the Beibu Gulf.(3) Dominant transition consistently exerts a positive driving effect, albeit with a diminishing influence over time; recessive transition acts as a positive driver in most counties, yet it presents a blocking effect in the sugarcane-dominated areas of southwestern Guangxi due to the relatively low proportion of grain-sown area.(4) Urbanization level emerges as the dominant driving factor, and interaction detection reveals that the synergistic effects of urbanization with agricultural economy and urbanization with farmers' income growth constitute the core interaction combinations.