Abstract: To address the issue of excessive fertilizer usage and low water efficiency in economic forest cultivation in Hexi Corridor irrigation area,Zaoyu pear was used as the research subject,and the water and salt regulation mode of submembrane dropper was used to conduct field drip irrigation experiment in the pear cultivation base of Zhangye Academy of Forestry.The 9 groups of water and fertilizer treatment were set,including 3 groups of irrigation gradient （irrigation quota of 3750,4500 and 5250 m³/hm²） and 3 medium fertilizers （organic fertilizer,water-soluble solid fertilizer and microbial fertilizer）.The growth and fruit indexes of pear were observed during the growing period with the actual production of flood irrigation and the normal application of diammonium phosphate as the control group CK.The impact of various combinations of water and fertilizer on the organic matter content in different rhizosphere soil layers,distribution of soil salt,shoot growth,and quality was investigated.The results showed that:（1） The effects of each treatment on soil organic matter content,soil salt,pear tree growth index,fruit quality and other indicators were not significant,but they were more advantageous than CK.（2） With the increase of drip irrigation,soil organic matter content showed an increasing trend.The content of soil organic matter under F₂ treatment was the highest,with an average value of 5.33 g/kg,1.28%higher than that under CK.That of F₁ treatment was 0.54%higher than CK,and that of F₃ treatment was 0.24%higher than CK.（3） The regulation of water and fertilizer had a significant effect on soil salinity,The conductivity of the soil leaching solution in each layer of each treatment exhibited a gradual decrease over time.The average soil extract conductivity under F₁,F₂ and F₃ treatments decreased by 6.22%,8.21%and 4.90%,respectively,compared to the control group （CK）.The F₂ treatment had the most significant reduction.（4） All treatments had positive effects on branch growth length and fruit quality.The optimal combination scheme was G₂F₂ combination.In conclusion,the combination of irrigation quota of 4500 m³/hm²,water-soluble solid fertilizer of 5000 kg/hm²,7 times irrigation during the growth period,and 2 times fertilization is optimal,which can provide a valuable reference for developing an optimal water and fertilizer management model for pear cultivation in Hexi Corridor irrigation area.